Anti-Phospho-Stat3 (Tyr705) Antibody, Recombinant Antibody
產(chǎn)品編號：RPTMB8A1
￥ 詢價
規(guī)格 100ug
產(chǎn)品名稱：Anti-Phospho-Stat3 (Tyr705) Antibody, Recombinant Antibody
克隆號：/
抗體亞型：/
經(jīng)驗證的應用：WB/IP/IHC/ChIP/IF/F
交叉反應：Human, Mouse, Rat, Monkey
特異性：Recognizes Phospho-Stat3 (Tyr705)
免疫原：Synthetic peptide
制備方法：/
來源：Recombinant Rabbit IgG
純化：Protein A purified
緩沖液：Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
偶聯(lián)物：Unconjugated
狀態(tài)：Liquid
運輸方式：This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
儲存條件：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
別稱：/
背景信息：The Stat3 transcription factor is an important signaling molecule for many cytokines and growth factor receptors and is required for murine fetal development. Research studies have shown that Stat3 is constitutively activated in a number of human tumors and possesses oncogenic potential and anti-apoptotic activities. Stat3 is activated by phosphorylation at Tyr705, which induces dimerization, nuclear translocation, and DNA binding. Transcriptional activation seems to be regulated by phosphorylation at Ser727 through the MAPK or mTOR pathways. Stat3 isoform expression appears to reflect biological function as the relative expression levels of Stat3α (86 kDa) and Stat3β (79 kDa) depend on cell type, ligand exposure, or cell maturation stage. It is notable that Stat3β lacks the serine phosphorylation site within the carboxy-terminal transcriptional activation domain.
全稱：/
說明書：待上傳